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Postdoctoral Associate-Tumor Microenvironment and Tumor Immunology (7277)

A postdoctoral associate position is available in the lab of Dr. Gary Ren to study tumor microenvironment and tumor immunology in cancer therapy resistance and metastatic relapse. Using genomic and proteomic approaches, cancer patient specimen analysis, and mouse models of diverse cancer types, Dr. Ren's lab focuses on elucidating how mesenchymal lineage cells (mesenchymal stem cells and fibroblasts) and immunoregulatory myeloid cells (neutrophils) modulate the adaptive immune responses in treatment resistance and metastatic relapse. These studies will take full advantage of the unique research platform at JAX, using patient-derived xenograft (PDX) tumors in humanized mouse models, with the research goal of developing novel strategies targeting tumor microenvironment to improve the efficacies of conventional cancer therapies and new therapeutics such as immunotherapy.
The Jackson Laboratory (JAX), located adjacent to Acadia National Park in coastal Maine, is a leading nonprofit biomedical research organization, and the Jackson Laboratory Cancer Center (JAXCC) is one of 69 NCI-designated Cancer Centers in US. JAX offers a unique research and training environment characterized by multidisciplinary scientific collaborations, exceptional educational programs, unparalleled mouse and genomic resources and outstanding core services.
For outstanding postdoctoral trainees, JAX has a Postdoctoral Scholar Program (http://education.jax.org/postdoc-scholar.html) which provides an intellectually rigorous opportunity for early career scientists to become critical thinkers in preparation for scientific research, policy and entrepreneurial positions. Additionally, JAX has joint graduate student programs with Tufts University and the University of Maine.
Required Skills
Highly motivated candidates with background/interests in molecular biology, cancer biology, and immunology are particularly encouraged to apply.
Required Experience
Applicants must have a PhD degree in cell biology, immunology or other similar disciplines.
To apply, please submit a cover letter describing past research accomplishments, research interests and career aspirations, a current CV, and the names of three references.



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