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Postdoctoral Associate - Computational Genetics & Systems Biology Approaches to Alzheimer’s Disease

The Kaczorowski Lab at The Jackson Laboratory is seeking a Postdoctoral Associate to investigate mechanisms of cognitive resilience to Alzheimer' disease using computational genetics and systems biology approaches. Our group is generating multi-scale data (DNA, RNA, protein, cell morphology, neural network maps and behavior) across the lifespan of 'humanized' mouse populations that model human Alzheimer's disease. The candidate will develop and iteratively test algorithms for analyses of these large-scale data sets using state-of-the-art computational methods to understand how both genetic factors combine with environmental factors (e.g. diet) to control resilience to disease-related processes in animal models and human studies. This position will strengthen ongoing collaborative work among investigators in the JAX Alzheimer's disease center.
The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research resources (e.g. The Nathan Shock Aging Center and Center for Novel Alzheimer's Disease Models), unparalleled mouse resources, and an outstanding training environment characterized by scientific collaboration and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Scientist Magazine polls repeatedly place The Jackson Laboratory among the top 15 "Best Places to Work in Academia" in the United States.
The successful candidate will be encouraged to develop an independent research program using the broad array of resources and expertise available to the Kaczorowski lab (https://www.jax.org/research-and-faculty/tools/scientific-research-services). Translational research collaborations in genomics-based, personalized medicine are fostered through our new JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.
Required Skills
Ability to plan, execute and analyze an independent research project as well as exceptional verbal and written communication skills. Preference given to self-motivated and career oriented individuals.
Required Experience
Required qualifications include a PhD in Neuroscience, Computational / Systems Biology, or a related field and a commitment to solving biological problems. Expertise in scientific programming languages including R, C/C++, Ruby, Perl, or Java is recommended. Expertise in neurological disease, particularly Alzheimer's disease is desired.
Candidates with three plus years of postdoctoral experience, and documented meritorious scientific accomplishments, may be qualified as an Associate Research Scientist per this posted position.
To apply, please submit (1) a cover letter describing past research accomplishments, research interests, and career goals, (2) a current CV, and (3) the contact information of three references, as one PDF file.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.



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